The dataset was produced as part of the European Space Agency (ESA) Climate Change Initiative+ (CCI+) precursors for aerosols and ozone project by the Royal Netherlands Meteorological Institute (KNMI). TROPOspheric Monitoring Instrument (TROPOMI) global tropospheric nitrogen dioxide (NO2) spatiotemporally averaged per month over a standard grid from May 2018 to December 2021. The dataset is provided in four different spatial resolutions: 0.2x0.2 (900x1800 grid cells), 0.5x0.5 (360x720), 1x1 (180x360), 2x2.5 (91x144) and includes auxilliary variables (e.g. cloud and surface properties, propagated level 3 uncertainties, averaging kernels). The data are provided in monthly netCDF files for each spatial resolution.The version number is 1.0. Data are available in NetCDF format. https://doi.org/10.5194/essd-17-4627-2025